PUBLISHED RESULTS
Recently the following basic results of researches of the National Registry were published.
Victor K. Ivanov, Anatoly F. Tsyb, Alexander P. Panfilov, Alexander M. Agapov, Oleg V. Kaidalov, Alexander M. Korelo, Ìarat A. Maksioutov, Sergey Y. Chekin, and Polina V. Kashcheyeva
Internationally, the upper limit of acceptable individualized risk from occupational exposure for nuclear industry workers is determined by the death probability 10-3 y-1. The same risk value of 10-3 y-1 is established by the radiation safety standards currently in force in Russia. The United Nations Scientific Committee on the Effects of Atomic Radiation has proposed the formulas for estimating individualized risk of developing cancer with allowance for radiation dose, age at exposure, attained age, and sex. This methodology is first applied to estimate individualized radiation risk for Russian nuclear industry workers (49,900 persons) who were monitored for radiation exposure through the use of personal dosimeters. The estimates show that in 2006 the threshold of
10-3 y-1 for individualized risk is exceeded for 755 persons, which is 1.6% of all workers covered by personal dose monitoring. The excess absolute risk (EAR) and attributable risk (AR) were estimated for all cancers, solid cancers, and leukemias.
V. K. Ivanov, A. I. Gorsky, V. V. Kashcheev, M. A. Maksioutov, K. A. Tumanov
The paper presents estimates for the latent period of the induction of radiogenic solid cancers among Chernobyl emergency workers (males) living in six central regions of Russia. The analysis is based on medical and dosimetry data gathered by the National Radiation and Epidemiological Registry over the time period from 1986 to 2005. The cohort includes 59,770 persons who stayed in the exposure zone (30-km zone around the Chernobyl nuclear power plant) in 1986-1987. There were 2,718 cases of solid tumors identified during the follow-up time in this cohort. The mean radiation dose in the cohort is 0.13 Gy. The radiation risk and latent period were estimated using the method of maximum likelihood. The excess relative risk per unit dose was found to be 0.96 (95% confidence interval (CI): 0.3–1.7) and the minimum latent period for induction of solid tumors is 4.0 years (95% CI: 3.3–4.9).
Ivanov V.K., Gorsky A.I., Maksioutov M.A., Tumanov K.A., Kashcheev V.V.
The paper discusses the results of analysis of radiation risks of thyroid cancers among the Chernobyl emergency workers (living in Russia) resulting from exposure to iodine radioisotopes. Due to the lack of documented doses from this source, the characteristics of the curve of this radionuclide decay were used for analysis. The analysis was performed by two independent methods: the exposed versus unexposed (the exposed are the emergency workers who worked in the 30-km zone during the first 65 days after the accident and the unexposed are those working there later) and the regression analysis based on the maximum likelihood method using the surrogate dose (period and time of stay in the 30-km zone during 131I decay). By both methods statistically significant estimates were derived for the relative radiation risk – 1.8 (1.2; 2.8 95% CI) and for the excess radiation risk per unit surrogate dose – 2.5 (0.2; 6.5 95% CI). The obtained results indicate that the follow-up of the emergency workers in relation to this issue should be continued.
In Russian
Ivanov V.K., Zamulaeva I.A., Kashcheeva P.V., Saenko A.S., Orlova N.B., Smirnova S.G.,
Korelo A.M., Gorsky A.I., Maksioutov M.À., Vaizer V.I.
In the study forming groups of potential cancer risk from occupational exposure to radiation with molecular and radiation epidemiological approaches is discussed. Frequency of gene mutations at TCR locus was measured in 320 professionals of the State Scientific Center of the Russian Federation Institute for Physics and Power Engineering named after A.I. Leypunsky. Average accumulated dose get by the workers was 100 mSv. Due to the use of radiation epidemiological approaches to defining the workers with the value of attributable radiation risk of 10% and more it was managed to increase the portion of people with increased level of gene mutations in the group. It is noted that the obtained results are preliminary because of limited statistical power of studies.
In Russian
Rozhko A.V., Vlasov O.K., Chunikhin L.A., Drozdov D.N.
A method for internal dose assessment in rural inhabitants living on contaminated territories of the Republic of Belarus had been developed. The method is based on the individual internal WBC-doses.
In Russian
Kashcheev V.V., Chekin S.Y., Maksioutov M.À., Tumanov K.A., Ivanov V.K.
A dependence of radiation risk of cancers in emergency accident workers of the Chernobyl accident on their age at exposure was estimated for the first time. Excess relative risk (ERR/Gy) was found to be 1.07 (95% CI: 0.49; 1.73) in the age group of 36-65 years. The value of ERR/Gy is considerably lower and statistically insignificant in the age group of 18-35 years, it is 0.11
(95% CI: -0.58; 0.95).
In Russian
Vlasov O.K, Shchukina N.V.
Updating of official technique of reconstruction of an all body internal irradiation dozes of Russian Federation inhabitants, undergone to radioactive fallout owing to ChNPP accident in 1986 is
executed. Updating is executed on the basis of official technique of reconstruction of internal thyroid doses of Russian Federation inhabitants on radioactive contamination territories owing to ChNPP accident in 1986. In this article there are basic ratio for calculation of 137Cs intake dynamics in a person organism are resulted due to inhalation and radio-contaminated food stuffs, 137Cs activity dynamics in a person organism and an all body internal dose. The general properties of the offered method are discussed.
In Russian
Drynova N.N., Vlasov O.K., Shchukina N.V., Ivanov V.K.
Prognosis of induction of radiation related solid cancers in population of the Kaluga oblast was made with the use of UNSCEAR model. It was found that the increase in the rate of all solid can-cers could be up to 1%. Calculated and actual data of the National Radiation and Epidemiological Registry were in good agreement. The contribution of radiation to increase of the rate of breast cancer in young women can be up to 4%.
In Russian
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