Preface
Part I. Emergency workers
Chapter 1. Background and basic principles of operation of the Russian National Medical
and Dosimetric Registry (RNMDR)
1.1. History of the Registry
1.2. Organizational structure, objectives and goals of the Registry
1.3. Monitored groups and operational procedures in the Registry
1.4. Primary source documents of the Registry
1.5. Specialized sub-registries of the RNMDR
1.6. Software and programming system of the Registry
1.7. Organizational and medical provision of the Registry
1.8. Dosimetry support for the Registry
Chapter 2. The cohort of the Chernobyl emergency workers within the RNMDR
Chapter 3. The health status of emergency workers based on the RNMDR data:
time trends of incidence and its nozological structure
3.1. Analysis of results of follow-up of male emergency workers resident in the territory
of the Russian Federation
3.2. Analysis of incidence rates in the Chernobyl emergency workers
3.3. Analysis of pattern of incidence in the Chernobyl emergency workers
3.4. Analysis of dose response of incidence in the Chernobyl emergency workers
3.5. Analysis of incidence rates in emergency workers in follow-up period 1997-2001
Chapter 4. Dosimetric data in the RNMDR for the Chernobyl emergency workers
4.1. Distribution of absorbed doses in emergency workers
4.2. Analysis of reliability of dosimetric data for emergency workers
4.3. Mean radiation doses for emergency workers
Chapter 5. Prediction of long-term stochastic effects
5.1. Prediction of mortality from radiogenic cancers in the cohort of emergency workers
5.2. Estimation of a possibility to determine radiation risks for the cohort
of emergency workers based on the RNMDR data
Chapter 6. Trends of cancer incidence among the Chernobyl emergency workers:
estimation of radiation risks
6.1. Analytical methods
6.2. Estimation of radiation risks of leukemia and thyroid cancer (cohort studies, 1986-1993)
6.3. Dose response of leukemias (cohort studies, 1986-1996)
6.4. Analysis of incidence of leukemia among emergency workers
(case control study, 1986-1993)
6.5. Estimation of radiation risks of solid cancers (cohort studies, 1986-1996)
6.6. Thyroid cancer incidence among emergency workers of the Chernobyl accident:
absence of dependence of radiation risks on external radiation dose
6.7. Dose response of leukemias (cohort studies, 1996-1998)
6.8. Radiation and epidemiological analysis for solid cancer incidence among nuclear workers who took part in recovery operations following the accident at the Chernobyl NPP
6.9. Estimation of radiation risks of solid cancers (cohort studies, 1991-2001)
Chapter 7. Radiation-epidemiological analysis of incidence of non-cancer diseases
among the Chernobyl emergency workers
7.1. Brief review of the literature on relationship of radiation exposure and non-cancer diseases
7.2. Characterization of the cohort
7.3. Analytical method and source of data
7.4. Estimation of the dose dependency for the main classes of non-cancer diseases
7.5. Estimation of the dose dependency for diseases of the circulatory system
7.6. Radiation-epidemiological analysis of cerebrovascular diseases in emergency workers
7.7. Elevated cataract rates in Chernobyl emergency workers of first 300 days
7.8. Estimation of the dose dependency for mental disorders
Chapter 8. Mortality among the Chernobyl emergency workers: estimation of radiation risks
8.1. Overview of studies of dose response relationship for mortality among
the exposed population
8.2. Analysis of dynamics and pattern of overall mortality among
the Chernobyl emergency workers
8.3. Study of dose response of the cancer mortality in emergency workers
8.4. Study of dose response of mortality from non-cancer diseases in emergency workers
Chapter 9. Lessons of Chernobyl: how to be better prepared for epidemiological
follow-up of population affected by major radiological accidents
9.1. Radiation disaster epidemiology as a particular branch of disaster epidemiology
9.2. WHO`s response to the Chernobyl accident with emphasis on epidemiological aspects
9.3. As a result of the Chernobyl experience the improvement of WHO`s capability
to respond to future radiological emergency
9.4. Approach for better preparedness to epidemiological follow-up of population
affected by major radiological accidents
Part II. Population
Chapter 1. Prediction of long-term stochastic effects: cancer incidence in exposed population
1.1. Model of radiation risks for cancer morbidity
1.2. Demographic data and doses for the population of the Bryansk oblast
1.3. Mathematical model for predicting radiation-induced risks
1.4. Prediction of radiation-induced cancers in the population of the Bryansk oblast
Chapter 2. Methodology for medical information quality control in large-scale information
systems used in health care sector as implemented in the Russian National
Medical and Dosimetric registry
2.1. Main areas of medical information quality control in the RNMDR system
2.2. Organization of gathering information on malignant neoplasms in the RNMDR
2.3. Quality of medical information in the RNMDR for the Bryansk, Kaluga,
Tula and Oryol oblasts
Chapter 3.Problem of thyroid cancer incidence in Russia after the Chernobyl accident
3.1. Problem of thyroid cancer incidence in Bryansk, Kaluga, Oryol and Tula oblasts:
estimation of radiation risks at the rayon level
3.2. Thyroid cancer incidence in children of the Bryansk oblast:
estimated radiation risks, 1991-2001 follow-up period
3.3. Thyroid cancer incidence among adolescents and adults in the Bryansk oblast
3.4. Thyroid cancer incidence among population of the Oryol oblast
Chapter 4. Radiation risks for leukemia incidence among residents of the Bryansk oblast
Chapter 5. Estimation of solid cancer incidence rate in the population of the most contaminated territories of Russia
5.1. Cancer incidence rate in the population of the contaminated territories:
projections and actual data
5.2. Estimation of possible dose response relationship of incidence rate of solid cancers
Conclusion
References
Authors: V.K. Ivanov, A.F. Tsyb, S.I. Ivanov, V.I. Pokrovsky, M.A. Maksioutov,
A.I. Gorski, O.K. Vlasov, A.P. Biryukov, O.V. Kaidalov, E.G. Matveenko,
S.E. Khait, Z.G. Kruglova, E.V. Kochergina, G.N. Souchkevitch, N.E. Meskikh, S.Y. Chekin, A.M. Korelo, A.M. Godko
